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Alcohol, Opioids, and Pain - From the Editors

Opioids and alcohol are both effective analgesics under certain pain conditions. However, although the analgesic or pain-relieving properties of opioids are well known, information about the use of alcohol and its potential for misuse in the context of pain management has begun to emerge more recently. Alcohol doses required to alleviate pain are commensurate with binge drinking,1 defined as...

Associations Between Socioeconomic Factors and Alcohol Outcomes

According to the World Health Organization (2014), alcohol consumption is responsible for approximately 5.9 percent of deaths worldwide and a global loss of 139 million disability-adjusted life-years. The alcohol-related disease burden is precipitated in part by acute intoxication, which decreases reaction time, perception and motor skills, and inhibitions and is thereby associated with an...

Epigenetics Glossary

Adipogenesis: Process of cell differentiation by which fat cells (i.e., adipocytes) are generated from precursor cells.

AMP/ATP ratio: Ratio of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) in the cell; ATP supplies the energy needed for many biochemical reactions; therefore, the AMP/ATP ratio reflects the cell’s energy level.

Apoptosis: Series of biochemical reactions occurring...

Under-Researched Demographics: Heavy Episodic Drinking and Alcohol-Related Problems Among Asian Americans

Treatment Interventions for Women With Alcohol Use Disorder

Women with alcohol use disorder (AUD) experience more barriers to AUD treatment and are less likely to access treatment than men with AUD. A literature review identified several barriers to women seeking help: low perception of a need for treatment; guilt and shame; co-occurring disorders; employment, economic, and health insurance disparities; childcare responsibilities; and fear of child...

Putting the Screen in Screening: Technology-Based Alcohol Screening and Brief Interventions in Medical Settings

Alcohol is strongly linked to the leading causes of adolescent and adult mortality and health problems, making medical settings such as primary care and emergency departments important venues for addressing alcohol use. Extensive research evidence supports the effectiveness of alcohol screening and brief interventions (SBIs) in medical settings, but this valuable strategy remains underused, with...

Drinking Across the Lifespan: Focus on Older Adults

In 2010, when the leading edge of the post–World War II “Baby Boom” reached age 65, the United States began a period of increased growth in its older adult population. By 2030, it is expected that there will be 72.1 million adults age 65 or older living in the United States, almost double the 2008 population. Those older adults will represent 19.3 percent of the U.S. population, compared with 12...

Age, Period, and Cohort Effects in Alcohol Use in the United States in the 20th and 21st Centuries: Implications for the Coming Decades

Introduction

Alcohol consumption, including any alcohol use; patterns of high-risk use, including binge drinking; and alcohol use disorder (AUD) incidence and prevalence, differs substantially over time and by life stage. Variation also occurs across demographic groups, and such differences themselves vary across time and place. In the first quarter of the 21st century, changes in incidence and...

The Burden of Alcohol Use: Excessive Alcohol Consumption and Related Consequences Among College Students

Since 1976, when the National Institute on Alcohol Abuse and Alcoholism (NIAAA) issued its first report on alcohol misuse by college students, research advances have transformed our understanding of excessive drinking on college campuses and the negative outcomes that follow from it. For instance, we now know that a broad array of factors influence whether a particular college student will choose...

The Epidemiology of Post-Traumatic Stress Disorder and Alcohol Use Disorder

For more than 40 years, research has shown that individuals with post-traumatic stress disorder (PTSD) use alcohol and experience alcohol use disorder (AUD) to a greater degree than those with no PTSD. AUD and PTSD have shown a durable comorbidity that has extended through decades and through changes in disorder definitions. Some research shows that veterans who have experienced PTSD have a high...