Search
Prevalence and Predictors of Adolescent Alcohol Use and Binge Drinking in the United States
In the United States, alcohol use typically begins and escalates during adolescence and young adulthood. To describe the historical and developmental trends in substance use in this age group, the Monitoring the Future (MTF) study (Johnston et al. 2012) was designed in 1975. Since then, this ongoing national-cohort sequential longitudinal study assessing the epidemiology and etiology of substance...
Many service members and veterans seeking treatment for alcohol problems have experienced the life-threatening stress of combat, many have post-traumatic stress disorder (PTSD), and many service members and veterans seeking treatment for PTSD have alcohol or other substance problems. Sensitivity to these issues can influence how a therapist relates to the patient and also has possible...
“Maturing Out” of Binge and Problem Drinking
Alcohol Use Disorder and Traumatic Brain Injury
In Utero Alcohol Exposure, Epigenetic Changes, and Their Consequences
Alcohol exposure of the developing embryo and fetus in utero can have a wide range of detrimental effects collectively referred to as fetal alcohol spectrum disorders (FASD). Researchers are intensively investigating the mechanisms that may contribute to alcohol’s effects on the developing organism and to the resulting consequences, particularly with respect to the cognitive and behavioral...
Alcohol Dependence and Genes Encoding α2 and γ1 GABAA Receptor Subunits
Even though the consequences of alcohol dependence (AD) clearly are devastating and obvious to observers, the molecular mechanisms involved in the development of the disease are far from clear and understood. The search for these mechanisms is made even more difficult by the vast number of genes, proteins, and pathways in the human body that potentially could be involved, and by the obvious...
“Maturing Out” of Binge and Problem Drinking
This article reviews literature aiming to explain the widespread reductions in binge and problem drinking that begin around the transition to young adulthood (i.e., “maturing out”). Whereas most existing literature on maturing out emphasizes contextual effects of transitions into adult roles and responsibilities, this article also reviews recent work demonstrating further effects of young adult...
Alcohol’s Effects on Lung Health and Immunity
People have been drinking alcoholic beverages for millennia, and alcohol consumption has played an important role throughout human history, being linked to ancient and modern religions, early medicine, and social occasions and celebrations. Although alcohol consumption is socially accepted across many cultures, heavy and prolonged alcohol intake can lead not only to physical dependence but also...
Alcoholic Myopathy: Pathophysiologic Mechanisms and Clinical Implications