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Nature and Treatment of Comorbid Alcohol Problems and Post-Traumatic Stress Disorder Among American Military Personnel and Veterans

Many service members and veterans seeking treatment for alcohol problems have experienced the life-threatening stress of combat, many have post-traumatic stress disorder (PTSD), and many service members and veterans seeking treatment for PTSD have alcohol or other substance problems. Sensitivity to these issues can influence how a therapist relates to the patient and also has possible implications...

Alcohol’s Burden on Immunity Following Burn, Hemorrhagic Shock, or Traumatic Brain Injury

The incidence of traumatic injury in alcohol-intoxicated individuals continues to escalate. According to the Centers for Disease Control and Prevention (2012a), more than 38 million American alcohol users consume 5 or more drinks on the same occasion (i.e., binge drink) and do so about 4 times per month. This behavior is highly conducive to unintentional or accidental traumatic injury, which...

The First Line of Defense: The Effects of Alcohol on Post-Burn Intestinal Barrier, Immune Cells, and Microbiome

Each year 2.5 million people die from alcohol abuse and its related morbidities worldwide, making alcohol related deaths among the highest preventable causes of death, and the greatest cause of premature death and disability in men between ages 15 and 59 (World Health Organization 2011). Alcohol abuse predisposes individuals to life-threatening conditions such as alcoholic liver disease (ALD)...

Alcohol and the Immune System - Editor's Note

Clinicians have long observed an association between excessive alcohol consumption and adverse immune-related health effects such as susceptibility to pneumonia. In recent decades, this association has been expanded to a greater likelihood of acute respiratory stress syndromes (ARDS), sepsis, alcoholic liver disease (ALD), and certain cancers; a higher incidence of postoperative complications; and...

Alcohol’s Effects on Lung Health and Immunity

People have been drinking alcoholic beverages for millennia, and alcohol consumption has played an important role throughout human history, being linked to ancient and modern religions, early medicine, and social occasions and celebrations. Although alcohol consumption is socially accepted across many cultures, heavy and prolonged alcohol intake can lead not only to physical dependence but also to...

Putting the Screen in Screening: Technology-Based Alcohol Screening and Brief Interventions in Medical Settings

Alcohol is strongly linked to the leading causes of adolescent and adult mortality and health problems, making medical settings such as primary care and emergency departments important venues for addressing alcohol use. Extensive research evidence supports the effectiveness of alcohol screening and brief interventions (SBIs) in medical settings, but this valuable strategy remains underused, with...

Community Indicators: Assessing the Impact of Alcohol Use on Communities

In the United States and other countries around the world, researchers have long been interested in community-level measurement of population health in the form of community indicators. Community indicators are measures that communicate information about a given dimension of a community’s well-being (Besleme and Mullin 1997). In the United States, the current popularity of community indicators can...

Chronic Diseases and Conditions Related to Alcohol Use

Alcohol has been a part of human culture for all of recorded history, with almost all societies in which alcohol is consumed experiencing net health and social problems (McGovern 2009; Tramacere et al. 2012b, c). With the industrialization of alcohol production and the globalization of its marketing and promotion, alcohol consumption and its related harms have increased worldwide (see Alcohol...

Epigenetic Targets for Reversing Immune Defects Caused by Alcohol Exposure

Extensive clinical and experimental data suggest that alcohol consumption has dose-dependent modulatory effects on the immune system that influence the two arms of the immune response (i.e., innate and adaptive immune responses). In many other organ systems, such as the brain and liver, alcohol consumption has been shown to alter factors that can modify gene expression without changing the DNA...

Alcohol and Stress in the Military

Problematic alcohol use within the United States military has been linked to substantial financial and productivity losses. Data from 2006 revealed that excessive alcohol consumption cost the U.S. military $1.12 billion per year (Harwood et al. 2009). Regarding medical expenditures, studies have found that excessive alcohol use by military members results in an annual cost of $425 million...