Behavioral Treatments for Alcohol Use Disorder and Post-Traumatic Stress Disorder
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Pathophysiology of the Effects of Alcohol Abuse on the Endocrine System
Alcohol’s Effects on the Brain: Neuroimaging Results in Humans and Animal Models
Biology, Genetics, and Environment: Underlying Factors Influencing Alcohol Metabolism
Epidemiological studies have demonstrated that drinking patterns and the prevalence of alcohol-related adverse consequences, including alcohol use disorder (AUD), differ substantially among racial/ethnic groups in the United States. For example, analyses comparing drinking patterns and their consequences among Whites, Blacks, Asians, and Hispanics found the following: Whites have the highest risk...
Neuroimmune Function and the Consequences of Alcohol Exposure
Advances in human neuroimaging have expanded our ability to understand the functioning of the brain, with particular recent advances fostering our analytic capacity to examine networks between the brain’s nerve cells (i.e., neurons) and neuroconnectivity (i.e., neural networks). Relevant to the field of alcoholism, several researchers recently have applied these strategies to groups at genetic...
Neuroplasticity and Predictors of Alcohol Recovery
Recovery from alcoholism is a complex and long-term process with high relapse rates. Therefore, understanding why people relapse has been critically important to improving treatment outcomes. To that end, researchers are looking for clinical and biological markers that predict relapse after treatment and to use those risk factors to develop effective treatments to reduce relapse rates. One...
Translating Alcohol Research: Opportunities and Challenges
More than 20 years ago, Daniel Koshland compared basic with applied research, stating: “Basic research is the type that is not always practical but often leads to great discoveries. Applied research refines these discoveries into useful products” (Koshland 1993). This statement implies that basic science does not have a direct impact on human health and disease or patient outcome but offers the...
A person with alcoholism engages in risky or dangerous drinking despite experiencing serious negative physical and social consequences. Such persistence in pursuing damaging behaviors suggests that the short-term “appetitive” results of drinking (such as intoxication and losing one’s inhibitions) have greater control over the alcoholic’s behavior than do the negative consequences. From a...