Advances in human neuroimaging have expanded our ability to understand the functioning of the brain, with particular recent advances fostering our analytic capacity to examine networks between the brain’s nerve cells (i.e., neurons) and neuroconnectivity (i.e., neural networks). Relevant to the field of alcoholism, several researchers recently have applied these strategies to groups at genetic...
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Alcohol consumption during pregnancy can interfere with both embryonic and fetal development, producing a wide range of outcomes that fall under the rubric of fetal alcohol spectrum disorders (FASD). FASD is the nondiagnostic umbrella term used to refer to the full range of effects that can occur following prenatal alcohol exposure. Such exposure can produce a variety of effects, including...
Advances in Electrophysiological Research
The discovery and recording of electrical activity (electroencephalography [EEG]) in the human brain in 1924 by the German physician Hans Berger (Collura 1993; Haas 2003) has led to numerous scientific breakthroughs and clinical applications (Borck 2005; Gloor 1994). Recording brain activity in humans using scalp electrodes provides a noninvasive, sensitive measure of ongoing brain function during...
Neuroimaging, particularly magnetic resonance imaging (MRI), has begun to tease apart the underlying mechanisms behind alcohol’s deleterious effects on the fetus and eventually may lead to earlier detection of what can be devastating child neurodevelopmental deficits. In 1968, researchers first reported an association between prenatal alcohol exposure and what can be persistent adverse cognitive...
Long-lasting changes in synaptic function (i.e., synaptic plasticity) have long been thought to contribute to information storage in the nervous system (Kandel et al. 2014; Lovinger 2010). Studies combining behavioral and physiological analyses offer strong evidence supporting this hypothesis (Kandel et al. 2014; Ramirez et al. 2014). On the one hand, this plasticity allows the organism to adapt...
Translating Alcohol Research: Opportunities and Challenges
More than 20 years ago, Daniel Koshland compared basic with applied research, stating: “Basic research is the type that is not always practical but often leads to great discoveries. Applied research refines these discoveries into useful products” (Koshland 1993). This statement implies that basic science does not have a direct impact on human health and disease or patient outcome but offers the...
Influence of Social Media on Alcohol Use in Adolescents and Young Adults
Participation in online social media Web sites (e.g., Facebook and Twitter) has skyrocketed in recent years and created a new environment in which adolescents and young adults may be exposed to and influenced by alcohol-related content. Thus, young people are exposed to and display pro-alcohol messages and images through online portrayals of drinking on personal pages as well as unregulated...
Electronic Feedback in College Student Drinking Prevention and Intervention
Alcohol consumption is prevalent among college students and can be associated with serious negative consequences. Several efficacious programs using one-on-one brief intervention techniques have been developed to target high-risk drinking by individual students, such as the Brief Alcohol Screening and Intervention for College Students (BASICS) (Dimeff et al. 1999). To reach a larger population (e...
Alcohol is strongly linked to the leading causes of adolescent and adult mortality and health problems, making medical settings such as primary care and emergency departments important venues for addressing alcohol use. Extensive research evidence supports the effectiveness of alcohol screening and brief interventions (SBIs) in medical settings, but this valuable strategy remains underused, with...
Ecological momentary assessment (EMA) has afforded several important advances in the field of alcohol research, including testing prominent models of alcohol abuse etiology in “high resolution.” Using high-tech methods for signaling and/or assessment, such as mobile electronic diaries, personal data assistants, and smartphones, EMA approaches potentially can improve understanding of precipitants...