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This issue of Alcohol Research: Current Reviews examines the public health impact of alcohol consumption beyond the role of alcohol use disorders alone (Room et al. 2005)—that is, it looks at the burden of disease. Determining impact hinges on accurate and consistent “measurements.” As demonstrated in the articles in this issue, impact typically is estimated based on three elements (Rehm et al...

Introduction

A central feature of substance use disorder (SUD) is the emergence of negative affective or emotional states that influence the motivational properties of misused substances.¹ Individual propensity to experience pain-related negative affect, for example, is hypothesized to be associated with the maintenance of both opioid use disorder (OUD) and alcohol use disorder (AUD). Chronic...

Sexually dimorphic effects of alcohol exposure throughout life have been documented in clinical and preclinical studies. In the past, rates of alcohol use disorder (AUD) were higher in men than in women, but over the past 10 years, the difference between sexes in prevalence of AUD and binge drinking has narrowed. Recent evidence adds to historical data regarding the influence of sex steroids on...

Although rates of alcohol and other substance use disorders in adolescents have been estimated for decades, little is known about the prevalence, pathways, and predictors of remission and long-term recovery among adolescents. This article provides an integrative review of the literature on youth recovery. A final selection of 39 relevant articles was grouped into five sections: treatment outcomes...

Exposure to varying forms of stress is an integral life experience that can provoke a variety of reactions. In research on alcohol, drug, and psychiatric disorders, the term “stress” often is understood to indicate any experience denoting adversity (Dohrenwend 2000). Stress exposures consist of external stimuli that are threatening or harmful; elicit fear, anxiety, anger, excitement, and/or...

Introduction

Abundant cross-sectional data indicate that alcohol use and related problems are accompanied by disruptions to sleep and circadian rhythms.¹ Alcohol's negative impacts on sleep are well established, especially in adults, and a smaller body of literature also reports alcohol's disruption of circadian rhythms.^2-4 Growing evidence supports sleep and circadian factors as influencing...

1Health Behavior Research and Training Institute, University of Texas at Austin, Austin, Texas

Introduction

Chronic pain increases the risk for development of alcohol use disorder (AUD). Given that acute alcohol consumption can reduce pain, humans sometimes drink alcohol for relief of pain. Chronic alcohol consumption, however, can increase pain sensitivity during withdrawal and facilitate pain sensitization related to comorbid pain conditions.¹ Ascending and descending nociceptive...

Even though the prevalence of alcohol use in the United States generally is lower among women compared with men (Substance Abuse and Mental Health Services Administration [SAMHSA] 2011), this gap has narrowed (Grucza et al. 2008). Furthermore, although women consume alcohol at lower levels than men, their body composition puts them at higher risk than men of developing some alcohol-related...