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Recovery in Special Emphasis Populations
The Synaptic Interactions of Alcohol and the Endogenous Cannabinoid System
Alcohol use disorder (AUD) is a chronic, relapsing brain disorder, characterized by a compromised ability to control alcohol use despite adverse occupational, social, or health consequences. Results from a 2019 National Survey on Drug Use and Health found that 5% of individuals over age 12 had AUD, affecting 14.5 million people in the United States. Alcohol and cannabis products are...
Alcohol Use As a Risk Factor in Infections and Healing: A Clinician's Perspective
Alcohol use and misuse have been part of human society for centuries. Early physicians recognized since the 1800s that alcohol produced not only impairment of the senses but also higher predisposition for tuberculosis. William Osler, the father of scientific medicine, reported in 1905 that patients who misused alcohol had higher predisposition to pneumonia (Osler 2001).
Between 2006 and 2010 in...
Racial/Ethnic Disparities in Mutual Help Group Participation for Substance Use Problems
Racial/ethnic minority groups comprise a large proportion of the U.S. population and evidence a substantial need for treatment of substance use disorder (SUD). Analysis of the most recent, reliable data available—the 2018 National Survey on Drug Use and Health (NSDUH)1—found that the prevalence of past-year SUD among those age 12 and older was higher among some racial/ethnic minority...
Surveys That Include Information Relevant to Binge Drinking
Biology, Genetics, and Environment: Underlying Factors Influencing Alcohol Metabolism
Epidemiological studies have demonstrated that drinking patterns and the prevalence of alcohol-related adverse consequences, including alcohol use disorder (AUD), differ substantially among racial/ethnic groups in the United States. For example, analyses comparing drinking patterns and their consequences among Whites, Blacks, Asians, and Hispanics found the following: Whites have the highest risk...
The Role of Innate Immunity in Alcoholic Liver Disease
Heavy consumption of alcohol poses a well-known health risk worldwide. Alcohol’s effects on health and well-being are numerous and include injuries and fatalities resulting from alcohol-induced incapacitation. Moreover, chronic and heavy alcohol consumption affects the integrity and function of vital tissues and organs, causing slow but significant structural and functional damage over time. One...
In Utero Alcohol Exposure, Epigenetic Changes, and Their Consequences
Alcohol exposure of the developing embryo and fetus in utero can have a wide range of detrimental effects collectively referred to as fetal alcohol spectrum disorders (FASD). Researchers are intensively investigating the mechanisms that may contribute to alcohol’s effects on the developing organism and to the resulting consequences, particularly with respect to the cognitive and behavioral...
