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Biobehavioral Interactions Between Stress and Alcohol
Maternal Substance Use: Consequences, Identification, and Interventions
A
Adinoff, B.
Clinical Laboratory Stressors Used to Study Alcohol–Stress Relationships
Vol. 34, No. 4, Pages 459–467
Agrawal, A.
Identifying Genetic Variation for Alcohol Dependence
Vol. 34, No. 3, Pages 274–281
Alim, T.N.
Resilience to Meet the Challenge of Addiction: Psychobiology and Clinical Considerations
Vol. 34, No. 4, Pages 506–515
Ames, G.M.
Prevention in the Military...
How Does Stress Lead to Risk of Alcohol Relapse?
It has long been known that stress increases the risk of alcohol relapse (Sinha 2001). Clinical observations, surveys, and epidemiological studies document an association between self-reports of stressors and subsequent return to drinking. Studies assessing alcohol relapse after treatment completion and discharge also indicate the contribution of highly stressful events independent of alcohol use...
“Those who cannot remember the past are condemned to repeat it.”
—George Santayana
Few observations in psychiatry have been documented as long and as consistently as the association between anxiety (and general negative affect) and the chronic misuse of alcohol. Research has shown that up to 50% of individuals receiving treatment for problematic alcohol use also met diagnostic criteria for one...
Neuroplasticity and Predictors of Alcohol Recovery
Recovery from alcoholism is a complex and long-term process with high relapse rates. Therefore, understanding why people relapse has been critically important to improving treatment outcomes. To that end, researchers are looking for clinical and biological markers that predict relapse after treatment and to use those risk factors to develop effective treatments to reduce relapse rates. One...
Epigenetics—Beyond the Genome in Alcoholism
Alcohol is one of the most widely used addictive drugs, and continued use and abuse can lead to the development of tolerance and dependence (Koob 2003a; Tabakoff et al. 1986). Numerous studies have shown that both genetic and environmental risk factors play a role in the development of alcoholism (Ducci and Goldman 2008; Edenberg and Foroud 2006; Farris et al. 2010). Genetic studies in both humans...
Binge Drinking’s Effects on the Developing Brain—Animal Models
Adolescence typically is a time of experimentation and emulation of adult behaviors, and many adolescents initiate alcohol and other drug (AOD) use during this developmental period. Brain development continues during adolescence, which could render the adolescent brain particularly vulnerable to alcohol’s effects. Consequently, adolescent alcohol exposure could result in long-lasting changes in...
Patterns of Cannabis and Alcohol Co-Use: Substitution Versus Complementary Effects
Use of alcohol and related problems cause significant global and individual health-related harms, and alcohol use is currently the third-leading cause of preventable death in the United States.1,2 Alcohol and cannabis are among the most commonly used psychoactive substances in the United States.3 Although concurrent use of alcohol and cannabis (i.e., co-use: defined as using both...
