Alcohol consumption during pregnancy can interfere with both embryonic and fetal development, producing a wide range of outcomes that fall under the rubric of fetal alcohol spectrum disorders (FASD). FASD is the nondiagnostic umbrella term used to refer to the full range of effects that can occur following prenatal alcohol exposure. Such exposure can produce a variety of effects, including...
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The Epidemiology of Post-Traumatic Stress Disorder and Alcohol Use Disorder
Alcohol Use Disorder and Antisocial and Borderline Personality Disorders
Introduction
The quest to understand the etiology, course, and treatment of alcohol use disorder (AUD) has given rise to an extensive body of work on identifying factors that contribute to these phenomena. Many of these factors, such as temperament and personality traits, are common to multiple psychiatric conditions, and some, such as variants of alcohol metabolizing genes, are specific to AUD...
Fetal Alcohol Spectrum Disorders: Awareness to Insight in Just 50 Years
Introduction
The establishment of the National Institute on Alcohol Abuse and Alcoholism (NIAAA) in 1971 was bracketed by three seminal papers that laid the groundwork for the field of fetal alcohol spectrum disorders (FASD) research. In 1968, Lemoine et al.1 described children with birth defects and neurodevelopmental disorders associated with prenatal alcohol exposure (PAE). This French...
Alcohol’s Effects on Breast Cancer in Women
Alcohol Use Disorder and Depressive Disorders
“Those who cannot remember the past are condemned to repeat it.”
—George Santayana
Few observations in psychiatry have been documented as long and as consistently as the association between anxiety (and general negative affect) and the chronic misuse of alcohol. Research has shown that up to 50% of individuals receiving treatment for problematic alcohol use also met diagnostic criteria for one...
Introduction
Although the awareness of the negative impact of prenatal alcohol exposure (PAE) was already alluded to in ancient writings1 and the impact of ethanol embryopathy in animal models was studied as early as 1910,2 the conceptualization of a syndrome associated with PAE was not recognized within modern medicine until the mid-20th century.3,4 The syndrome or disorder was not uniformly...
Alcohol Use Disorder and Schizophrenia or Schizoaffective Disorder
Introduction
Schizophrenia and schizoaffective disorder are heterogeneous psychotic disorders that often cause significant disability, with symptoms that include delusions, hallucinations, disorganization, and cognitive impairment.1 In schizoaffective disorder, the psychotic symptoms are present, along with mood episodes of depression or mania.2 People with these schizophrenia spectrum disorders...
Alcohol Use Disorder and Co-Occurring Mental Health Conditions - From the Editors
This issue of Alcohol Research: Current Reviews (ARCR) delves into studies on co-occurring alcohol use disorder (AUD) and mental health conditions, exploring how this co-occurrence affects symptom severity, prognosis, and outcomes. Increased risk because of co-occurrence, challenges because of disorder heterogeneity, and efficacy of treatment interventions are reviewed.
Among people with AUD...