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Influence of Alcohol on the Intestinal Immune System

Key Takeaways

  • Chronic alcohol consumption disrupts the intestinal barrier, causing dysbiosis, increased mucus thickness, and reduced antimicrobial peptides. This promotes bacterial translocation and systemic inflammation, which contribute to alcohol-associated liver disease (ALD).
  • Alcohol alters the intestinal immune system by disrupting the balance between immune tolerance and activation. This...

ARCR Editorial Staff

NIAAA/NIH Staff

Pamela Wernett, Ph.D., P.M.P.
Editor in Chief and Contracting Officer’s Representative

Pamela joined ARCR in 2018 as an Associate Editor and advanced to Editor in Chief for the journal in 2021. She has managed the journal contract with IQ Solutions as the Contracting Officer’s Representative since 2020. Pamela also serves as a Senior Health Science Policy Analyst within NIAAA’s...