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Area-Level Social Determinants of Alcohol-Related Mortality: Knowledge Gaps and Implications for Community Health

Key Takeaways

  • The literature on social determinants of alcohol-related mortality includes many studies focused on area-level determinants of alcohol-involved motor vehicle crashes and cirrhosis or liver disease mortality.
  • Extant research highlights the benefits of stronger alcohol policies and the importance of socioeconomic conditions as determinants of alcohol-related mortality.
  • Substantial gaps in...

Oppression-Based Stress and Alcohol Inequities Among Sexual and Gender Minority People: An Intersectional Multilevel Framework

Introduction

Sexual minority (e.g., lesbian, gay, bisexual, queer, asexual) and gender minority (e.g., transgender, nonbinary, other gender-diverse) people are at heightened risk for alcohol use, hazardous drinking,[*] and alcohol use disorder (AUD) compared to their heterosexual and cisgender counterparts.2-6 (For definitions of various sexual and gender minority [SGM] populations, see, for...

Alcohol, HMGB1, and Innate Immune Signaling in the Brain

Introduction

Alcohol intoxication alters neuronal networks that markedly impact impulsiveness, balance, and other important brain functions. Although acute intoxication has immediate dangers, alcohol use disorder (AUD) has a lasting impact on individuals and families. AUD is considered a chronic relapsing disease linked to cycles of intoxication often initiated in adolescence that change neuronal...

Are Cisgender Women and Transgender and Nonbinary People Drinking More During the COVID-19 Pandemic? It Depends.

Introduction

Although historically cisgender women (i.e., women whose sex assigned at birth is consonant with their gender) in the United States have had lower levels of alcohol consumption than cisgender men, recent analyses of historical and cohort data suggest that overall gender differences are narrowing.1 This narrowing is largely due to substantial increases in cisgender women's alcohol use...

Looking Back, Looking Forward: Current Medications and Innovative Potential Medications to Treat Alcohol Use Disorder

Introduction

According to national surveys, more than 85% of U.S. adults have consumed alcohol at some point in their lifetime, and about 70% did so in the last year.1 Most individuals drink responsibly and without adverse effects. However, a substantial proportion of people misuse alcohol.1,2 Drinking patterns associated with alcohol misuse include binge drinking, heavy drinking, and high...

Age, Period, and Cohort Effects in Alcohol Use in the United States in the 20th and 21st Centuries: Implications for the Coming Decades

Introduction

Alcohol consumption, including any alcohol use; patterns of high-risk use, including binge drinking; and alcohol use disorder (AUD) incidence and prevalence, differs substantially over time and by life stage. Variation also occurs across demographic groups, and such differences themselves vary across time and place. In the first quarter of the 21st century, changes in incidence and...

Alcohol, Opioids, and Pain - From the Editors

Opioids and alcohol are both effective analgesics under certain pain conditions. However, although the analgesic or pain-relieving properties of opioids are well known, information about the use of alcohol and its potential for misuse in the context of pain management has begun to emerge more recently. Alcohol doses required to alleviate pain are commensurate with binge drinking,1 defined as...

Alcohol Use Disorder: The Role of Medication in Recovery

Introduction

It is estimated that nearly 14.6 million Americans currently meet the diagnostic criteria for alcohol use disorder (AUD)1 included in the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5),2 and approximately 88,000 die from alcohol-related causes in the United States each year.3 An older term, “alcohol dependence,” is equivalent to the DSM-5 criteria for AUD of...

Alcohol-Related Disparities Among Women: Evidence and Potential Explanations

Although research on alcohol-related disparities among women is a highly understudied area, evidence shows that racial/ethnic minority women, sexual minority women, and women of low socioeconomic status (based on education, income, or residence in disadvantaged neighborhoods) are more likely to experience alcohol-related problems. These problems include alcohol use disorder, particularly after...