Skip to main content
U.S. flag

An official website of the United States government

Search

Text version of the flow diagram listing the genetic, neural, and behavioral changes associated with both maladaptive and adaptive stress responses

Flow diagram. Top level: Stress. Responses to stress include maladaptive stress response and adaptive stress response. Maladaptive stress response leads to susceptible phenotype, composed of Brain Activity: HPA axis dysregulation, increased VTA, mPFC, amygdala activity, and increased NAc, cingulate cortex volumes; Genetic Profile: increased expression of FKNP5 and CRH genes, decreased BDNF and IL...