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Abundant cross-sectional data indicate that alcohol use and related problems are accompanied by disruptions to sleep and circadian rhythms.1 Alcohol's negative impacts on sleep are well established, especially in adults, and a smaller body of literature also reports alcohol's disruption of circadian rhythms.2-4 Growing evidence supports sleep and circadian factors as influencing...
Drinking Across the Lifespan: Focus on Older Adults
In 2010, when the leading edge of the post–World War II “Baby Boom” reached age 65, the United States began a period of increased growth in its older adult population. By 2030, it is expected that there will be 72.1 million adults age 65 or older living in the United States, almost double the 2008 population. Those older adults will represent 19.3 percent of the U.S. population, compared with 12...
Genes Encoding Enzymes Involved in Ethanol Metabolism
The duration and extent of the body’s exposure to beverage alcohol (i.e., ethanol) is the primary determinant of ethanol’s pleiotropic effects on human health (Edenberg 2007). The time course of its concentration and the concentration of its byproducts in the tissues and the circulation, and, consequently, its effects, are determined mainly by the rate of ethanol’s processing (i.e., metabolism) in...
Biology, Genetics, and Environment: Underlying Factors Influencing Alcohol Metabolism
Epidemiological studies have demonstrated that drinking patterns and the prevalence of alcohol-related adverse consequences, including alcohol use disorder (AUD), differ substantially among racial/ethnic groups in the United States. For example, analyses comparing drinking patterns and their consequences among Whites, Blacks, Asians, and Hispanics found the following: Whites have the highest risk...
Alcohol and Stress in the Military
Problematic alcohol use within the United States military has been linked to substantial financial and productivity losses. Data from 2006 revealed that excessive alcohol consumption cost the U.S. military $1.12 billion per year (Harwood et al. 2009). Regarding medical expenditures, studies have found that excessive alcohol use by military members results in an annual cost of $425 million...
For the past 25 years, a growing number of U.S. states have been progressively legalizing cannabis markets, first through the early adoption of medical cannabis laws, which enabled the purchase and possession of cannabis for specific medicinal purposes, and then more recently through laws regarding adult (i.e., “recreational”) use of cannabis. As of May 2021, more than 70% of U.S...
Binge Drinking’s Effects on the Body
Behavioral Treatments for Alcohol Use Disorder and Post-Traumatic Stress Disorder
Alcoholic Liver Disease: Pathogenesis and Current Management
